GBP3 Exhibits antiviral activity against influenza virus. Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Hydrolase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p22.2
Cellular Component:  cytoplasm; cytosol; Golgi membrane; perinuclear region of cytoplasm
Molecular Function:  GTP binding; GTPase activity; protein binding; protein homodimerization activity
Biological Process:  cellular response to interleukin-1; cellular response to tumor necrosis factor; defense response to virus
Reference #:  Q9H0R5 (UniProtKB)
Alt. Names/Synonyms: DKFZp686E0974; DKFZp686L15228; FLJ10961; GBP-3; GBP3; GTP-binding protein 3; Guanine nucleotide-binding protein 3; guanylate binding protein 3; Guanylate-binding protein 3; guanylate-binding protein 3 delta C
Gene Symbols: GBP3
Molecular weight: 68,114 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene