FBF1 Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. 6 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component:  centriole; centrosome; ciliary transition fiber; cytosol; spindle pole
Molecular Function:  protein binding
Biological Process:  apical junction assembly; ciliary basal body-plasma membrane docking; cilium assembly; establishment of epithelial cell polarity
Reference #:  Q8TES7 (UniProtKB)
Alt. Names/Synonyms: Alb; albatross; Fas (TNFRSF6) binding factor 1; Fas binding protein 1; Fas-binding factor 1; FBF-1; FBF1; FLJ00103; FLJ13996; KIAA1863
Gene Symbols: FBF1
Molecular weight: 125,446 Da
Basal Isoelectric point: 6.62  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene