RSKL1 May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: AGC group; EC; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); RSKL family
Chromosomal Location of human Ortholog: 1q32.3
Cellular Component:  early endosome; endosome; lysosome; membrane
Molecular Function:  ATP binding; phosphatidylinositol binding; protein binding; protein serine kinase activity; protein serine/threonine kinase activity
Biological Process:  protein phosphorylation; signal transduction
Reference #:  Q96S38 (UniProtKB)
Alt. Names/Synonyms: 52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1; ribosomal protein S6 kinase C1; Ribosomal protein S6 kinase delta-1; ribosomal protein S6 kinase, 52kDa, polypeptide 1; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK118; RPS6KC1; RSKL1; S6K-delta-1; S6PKh1; SPHK1-binding protein
Gene Symbols: RPS6KC1
Molecular weight: 118,682 Da
Basal Isoelectric point: 4.76  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein