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RSKL1
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: AGC group; EC 2.7.11.1; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); RSKL family |
| Chromosomal Location of human Ortholog: 1q32.3 |
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Cellular Component:
early endosome; endosome; lysosome; membrane
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Molecular Function:
ATP binding; phosphatidylinositol binding; protein binding; protein serine kinase activity; protein serine/threonine kinase activity
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Biological Process:
protein phosphorylation; signal transduction
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Reference #:
Q96S38
(UniProtKB)
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Alt. Names/Synonyms: 52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1; ribosomal protein S6 kinase C1; Ribosomal protein S6 kinase delta-1; ribosomal protein S6 kinase, 52kDa, polypeptide 1; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK118; RPS6KC1; RSKL1; S6K-delta-1; S6PKh1; SPHK1-binding protein
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Gene Symbols: RPS6KC1
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Molecular weight:
118,682 Da
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Basal Isoelectric point:
4.76
Predict pI for various phosphorylation states
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