PKN3 Contributes to invasiveness in malignant prostate cancer. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues. Note: This description may include information from UniProtKB.
Protein type: AGC group; EC 2.7.11.13; Kinase, protein; PKN family; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 2|2 B
Cellular Component:  cytoplasm; nucleus
Molecular Function:  ATP binding; GTP-Rho binding; kinase activity; nucleotide binding; protein kinase activity; protein kinase C activity; protein serine/threonine kinase activity; transferase activity
Biological Process:  epithelial cell migration; intracellular signal transduction; peptidyl-serine phosphorylation; phosphorylation; protein phosphorylation; signal transduction
Reference #:  Q8K045 (UniProtKB)
Alt. Names/Synonyms: AW209115; BC034126; MGC31699; OTTMUSP00000018153; Pkn3; Pknbeta; protein kinase N3; Protein kinase PKN-beta; protein kinase PKNbeta; Protein-kinase C-related kinase 3; Serine/threonine-protein kinase N3
Gene Symbols: Pkn3
Molecular weight: 97,881 Da
Basal Isoelectric point: 9.06  Predict pI for various phosphorylation states
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PKN3

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene