BMP15
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. Belongs to the TGF-beta family. Note: This description may include information from UniProtKB.
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Protein type: Cytokine; Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: Xp11.22 |
Cellular Component:
endoplasmic reticulum lumen; extracellular space
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Molecular Function:
cytokine activity; growth factor activity
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Biological Process:
female gamete generation
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Disease: Ovarian Dysgenesis 2
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Reference #:
O95972
(UniProtKB)
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Alt. Names/Synonyms: BMP-15; BMP15; Bone morphogenetic protein 15; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2; POF4
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Gene Symbols: BMP15
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Molecular weight:
45,055 Da
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Basal Isoelectric point:
9.28
Predict pI for various phosphorylation states
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CST Pathways:
ESC Pluripotency and Differentiation
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Wnt/ß-Catenin Signaling
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