GTF2E1
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. Belongs to the TFIIE alpha subunit family. Note: This description may include information from UniProtKB.
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Protein type: Transcription initiation complex |
Chromosomal Location of rat Ortholog: 11q21 |
Cellular Component:
cytosol; nucleoplasm; nucleus; transcription factor TFIID complex; transcription factor TFIIE complex
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Molecular Function:
molecular adaptor activity; RNA polymerase II general transcription initiation factor activity
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Biological Process:
transcription by RNA polymerase II; transcription open complex formation at RNA polymerase II promoter
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Reference #:
Q4FZQ9
(UniProtKB)
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Alt. Names/Synonyms: general transcription factor IIE, polypeptide 1 (alpha subunit); general transcription factor IIE, polypeptide 1, alpha; Gtf2e1; Gtf2e1 protein
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Gene Symbols: Gtf2e1
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Molecular weight:
35,749 Da
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Basal Isoelectric point:
4.32
Predict pI for various phosphorylation states
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CST Pathways:
Protein Acetylation
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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