NDR2
Involved in the regulation of structural processes in differentiating and mature neuronal cells. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. Ubiquitously expressed with highest levels observed in the thymus. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: AGC group; EC 2.7.11.1; Kinase, protein; NDR family; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor) |
Chromosomal Location of human Ortholog: 12p11.23 |
Cellular Component:
actin cytoskeleton; cytoplasm; cytosol; glutamatergic synapse; membrane
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Molecular Function:
actin binding; ATP binding; magnesium ion binding; protein binding; protein serine kinase activity; protein serine/threonine kinase activity
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Biological Process:
intracellular signal transduction; peptidyl-serine phosphorylation; postsynapse organization; protein phosphorylation; regulation of cellular component organization
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Reference #:
Q9Y2H1
(UniProtKB)
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Alt. Names/Synonyms: KIAA0965; NDR2; NDR2 protein kinase; nuclear Dbf2-related 2; Nuclear Dbf2-related kinase 2; serine/threonine kinase 38 like; Serine/threonine-protein kinase 38-like; ST38L; STK38L
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Gene Symbols: STK38L
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Molecular weight:
54,003 Da
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Basal Isoelectric point:
6.36
Predict pI for various phosphorylation states
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