MAST1 Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. Note: This description may include information from UniProtKB.
Protein type: AGC group; EC; Kinase, protein; MAST family; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 19p13.13
Cellular Component:  cytoplasm; cytoskeleton; plasma membrane
Molecular Function:  ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activity
Biological Process:  cytoskeleton organization; intracellular signal transduction; protein phosphorylation
Disease: Mega-corpus-callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations
Reference #:  Q9Y2H9 (UniProtKB)
Alt. Names/Synonyms: KIAA0973; MAST1; microtubule associated serine/threonine kinase 1; Microtubule-associated serine/threonine-protein kinase 1; SAST; SAST170; syntrophin associated serine/threonine kinase; Syntrophin-associated serine/threonine-protein kinase
Gene Symbols: MAST1
Molecular weight: 170,677 Da
Basal Isoelectric point: 8.67  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene