NUDT22 Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose. Belongs to the Nudix hydrolase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 11q13.1
Cellular Component:  nucleoplasm
Molecular Function:  metal ion binding; protein binding; UDP-sugar diphosphatase activity
Reference #:  Q9BRQ3 (UniProtKB)
Alt. Names/Synonyms: MGC13045; Nucleoside diphosphate-linked moiety X motif 22; NUD22; nudix (nucleoside diphosphate linked moiety X)-type motif 22; nudix hydrolase 22; Nudix motif 22; NUDT22; UDPG pyrophosphatase; UGPPase; Uridine diphosphate glucose pyrophosphatase NUDT22
Gene Symbols: NUDT22
Molecular weight: 32,580 Da
Basal Isoelectric point: 4.99  Predict pI for various phosphorylation states
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NUDT22

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  Ensembl Protein