| NUDT22 Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose. Belongs to the Nudix hydrolase family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB. |
| Chromosomal Location of human Ortholog: 11q13.1 |
| Cellular Component: nucleoplasm |
| Molecular Function: metal ion binding; protein binding; UDP-sugar diphosphatase activity |
| Reference #: Q9BRQ3 (UniProtKB) |
| Alt. Names/Synonyms: MGC13045; Nucleoside diphosphate-linked moiety X motif 22; NUD22; nudix (nucleoside diphosphate linked moiety X)-type motif 22; nudix hydrolase 22; Nudix motif 22; NUDT22; UDPG pyrophosphatase; UGPPase; Uridine diphosphate glucose pyrophosphatase NUDT22 |
| Gene Symbols: NUDT22 |
| Molecular weight: 32,580 Da |
| Basal Isoelectric point: 4.99 Predict pI for various phosphorylation states |
| Select Structure to View Below |
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NUDT22 |
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Cross-references to other databases:
AlphaFold
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STRING
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cBioPortal
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Wikipedia
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neXtProt
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Protein Atlas
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BioGPS
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Pfam
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