CANT1 Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP Belongs to the apyrase family. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Endoplasmic reticulum; Hydrolase; Membrane protein, integral; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine
Chromosomal Location of Human Ortholog: 11 E2|11 83.15 cM
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; integral component of membrane; membrane
Molecular Function:  adenosine-diphosphatase activity; calcium ion binding; guanosine-diphosphatase activity; hydrolase activity; metal ion binding; nucleoside-diphosphatase activity; protein homodimerization activity; uridine-diphosphatase activity
Biological Process:  proteoglycan biosynthetic process; ribonucleoside diphosphate catabolic process
Reference #:  Q8VCF1 (UniProtKB)
Alt. Names/Synonyms: 5830420C20Rik; Apy1h; apyrase 1, homolog (C. lectularius); Apyrase homolog; Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase; calcium activated nucleotidase 1; Cant1; D11Bwg0554e; Entpd8; OTTMUSP00000004177; OTTMUSP00000004178; OTTMUSP00000004297; SCAN-1; Shapy; Soluble calcium-activated nucleotidase 1
Gene Symbols: Cant1
Molecular weight: 45,652 Da
Basal Isoelectric point: 6.28  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene