Dele1 Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation. Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 5q31.3
Cellular Component:  mitochondrion
Molecular Function:  protein binding
Biological Process:  extrinsic apoptotic signaling pathway via death domain receptors; regulation of cysteine-type endopeptidase activity involved in apoptotic process
Reference #:  Q14154 (UniProtKB)
Alt. Names/Synonyms: DAP3 binding cell death enhancer 1; DAP3-binding cell death enhancer 1; DAP3-binding cell death enhancer 1 short form; DAP3-binding cell death enhancer 1, long form; Death ligand signal enhancer; DELE; Dele1; DELE1(L); DELE1(S); hypothetical protein LOC9812; K0141; KIAA0141; S-DELE1; Uncharacterized protein KIAA0141, mitochondrial
Gene Symbols: DELE1
Molecular weight: 55,920 Da
Basal Isoelectric point: 9.37  Predict pI for various phosphorylation states
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Dele1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein