PTPN20A
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Present in many cell lines (at protein level). Widely expressed. 15 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Cancer Testis Antigen (CTA); EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor) |
Chromosomal Location of rat Ortholog: 16p16 |
Cellular Component:
centriolar satellite; cytoplasm; cytoplasmic side of plasma membrane; microtubule; microtubule organizing center; nucleus
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Molecular Function:
protein tyrosine phosphatase activity
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Biological Process:
protein dephosphorylation
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Reference #:
A1L1L3
(UniProtKB)
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Alt. Names/Synonyms: CT 126; protein tyrosine phosphatase, non-receptor type 20; PTN20; Ptpn20; PTPN20A; Tyrosine-protein phosphatase non-receptor type 20
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Gene Symbols: Ptpn20
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Molecular weight:
48,580 Da
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Basal Isoelectric point:
6.14
Predict pI for various phosphorylation states
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