TUBG1 Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. Belongs to the tubulin family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of human Ortholog: 17q21.2
Cellular Component:  apical part of cell; cell leading edge; centriole; centrosome; ciliary basal body; condensed nuclear chromosome; cytoplasm; cytoplasmic microtubule; cytosol; gamma-tubulin complex; non-motile cilium; pericentriolar material; polar microtubule; recycling endosome
Molecular Function:  GTPase activity; identical protein binding; protein binding
Biological Process:  ciliary basal body-plasma membrane docking; cytoplasmic microtubule organization; G2/M transition of mitotic cell cycle; meiotic spindle organization; regulation of G2/M transition of mitotic cell cycle
Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 4
Reference #:  P23258 (UniProtKB)
Alt. Names/Synonyms: CDCBM4; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; TBG1; TUBG; TUBG1; TUBGCP1; tubulin gamma 1; Tubulin gamma-1 chain; tubulin, gamma 1; tubulin, gamma polypeptide
Gene Symbols: TUBG1
Molecular weight: 51,170 Da
Basal Isoelectric point: 5.75  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene