DRAK2 Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. Note: This description may include information from UniProtKB.
Protein type: CAMK group; DAPK family; EC 2.7.11.1; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 1|1 C1.1
Cellular Component:  actin cytoskeleton; membrane; nucleus; plasma membrane
Molecular Function:  ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
Biological Process:  apoptotic process; intracellular signal transduction; phosphorylation; positive regulation of fibroblast apoptotic process; programmed cell death; protein autophosphorylation; protein phosphorylation
Reference #:  Q8BG48 (UniProtKB)
Alt. Names/Synonyms: 3110009A03Rik; AI120141; DAP kinase-related apoptosis-inducing protein kinase 2; Dra; Drak2; OTTMUSP00000023815; serine/threonine kinase 17b (apoptosis-inducing); Serine/threonine-protein kinase 17B; ST17B; Stk17b
Gene Symbols: Stk17b
Molecular weight: 41,983 Da
Basal Isoelectric point: 5.18  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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DRAK2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene