RASGEF1B Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro). 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Ras
Chromosomal Location of Human Ortholog: 4q21.21
Cellular Component:  early endosome; late endosome; midbody
Molecular Function:  Ras guanyl-nucleotide exchange factor activity
Biological Process:  positive regulation of GTPase activity; small GTPase mediated signal transduction
Reference #:  Q0VAM2 (UniProtKB)
Alt. Names/Synonyms: FLJ31695; GPI gamma-4; GPI-gamma 4; GPIG4; MGC46251; Ras-GEF domain-containing family member 1B; RasGEF domain family member 1B; RasGEF domain family, member 1B; RASGEF1B; RGF1B
Gene Symbols: RASGEF1B
Molecular weight: 55,359 Da
Basal Isoelectric point: 8.19  Predict pI for various phosphorylation states
CST Pathways:  GPCR Signaling to MAPKs
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein