RBAK
May repress E2F-dependent transcription. May promote AR-dependent transcription. Belongs to the krueppel C2H2-type zinc-finger protein family. Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: C2H2-type zinc finger protein |
Chromosomal Location of mouse Ortholog: 5|5 G2 |
Cellular Component:
nucleoplasm; nucleus
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Molecular Function:
DNA-binding transcription repressor activity, RNA polymerase II-specific; metal ion binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding
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Biological Process:
negative regulation of transcription by RNA polymerase II; regulation of DNA-templated transcription
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Reference #:
Q8BQC8
(UniProtKB)
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Alt. Names/Synonyms: RB-associated KRAB repressor; RB-associated KRAB zinc finger; RB-associated KRAB zinc finger protein; Rbak; Zinc finger protein 769; Znf769
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Gene Symbols: Rbak
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Molecular weight:
81,675 Da
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Basal Isoelectric point:
6.81
Predict pI for various phosphorylation states
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