RBAK May repress E2F-dependent transcription. May promote AR-dependent transcription. Belongs to the krueppel C2H2-type zinc-finger protein family. Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of human Ortholog: 7p22.1
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; zinc ion binding
Biological Process:  negative regulation of DNA-templated transcription; regulation of DNA-templated transcription; regulation of transcription by RNA polymerase II
Reference #:  Q9NYW8 (UniProtKB)
Alt. Names/Synonyms: hRBaK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger; RB-associated KRAB zinc finger protein; RBAK; Zinc finger protein 769; ZNF769
Gene Symbols: RBAK
Molecular weight: 82,995 Da
Basal Isoelectric point: 7.02  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein