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RBAK
May repress E2F-dependent transcription. May promote AR-dependent transcription. Belongs to the krueppel C2H2-type zinc-finger protein family. Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: C2H2-type zinc finger protein |
| Chromosomal Location of human Ortholog: 7p22.1 |
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Cellular Component:
nucleoplasm; nucleus
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Molecular Function:
DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; zinc ion binding
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Biological Process:
negative regulation of DNA-templated transcription; regulation of DNA-templated transcription; regulation of transcription by RNA polymerase II
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Reference #:
Q9NYW8
(UniProtKB)
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Alt. Names/Synonyms: hRBaK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger; RB-associated KRAB zinc finger protein; RBAK; Zinc finger protein 769; ZNF769
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Gene Symbols: RBAK
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Molecular weight:
82,995 Da
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Basal Isoelectric point:
7.02
Predict pI for various phosphorylation states
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