RFC5 The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Belongs to the activator 1 small subunits family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 12q24.23
Cellular Component:  DNA replication factor C complex; nucleoplasm; nucleus
Molecular Function:  ATP binding; DNA clamp loader activity; enzyme binding; protein binding; single-stranded DNA-dependent ATPase activity
Biological Process:  bypass DNA synthesis; DNA damage response, detection of DNA damage; DNA repair; DNA replication; error-prone postreplication DNA repair; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 5'-to lesion; telomere maintenance via semi-conservative replication; transcription-coupled nucleotide-excision repair
Reference #:  P40937 (UniProtKB)
Alt. Names/Synonyms: A1 36 kDa subunit; Activator 1 36 kDa subunit; Activator 1 subunit 5; MGC1155; replication factor C (activator 1) 5, 36.5kDa; Replication factor C 36 kDa subunit; Replication factor C subunit 5; RF-C 36 kDa subunit; RFC, 36.5 kD subunit; RFC36; RFC5
Gene Symbols: RFC5
Molecular weight: 38,497 Da
Basal Isoelectric point: 6.72  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene