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RASGRP3
Guanine nucleotide exchange factor (GEF) for Ras and Rap1. Belongs to the RASGRP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GEF; GEF, Ras |
| Chromosomal Location of rat Ortholog: 6q12-q13 |
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Cellular Component:
cytoplasm; cytosol; guanyl-nucleotide exchange factor complex; perinuclear region of cytoplasm; plasma membrane
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Molecular Function:
calcium ion binding; GTPase activator activity; guanyl-nucleotide exchange factor activity; kinase binding; small GTPase binding
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Biological Process:
positive regulation of GTPase activity; Ras protein signal transduction; regulation of GTPase activity
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Reference #:
NP_001101479
(RefSeq)
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Alt. Names/Synonyms: RAS guanyl releasing protein 3; RAS guanyl releasing protein 3 (calcium and DAG-regulated); RAS, guanyl releasing protein 3; Rasgrp3
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Gene Symbols: Rasgrp3
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Molecular weight:
68,292 Da
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Basal Isoelectric point:
6.41
Predict pI for various phosphorylation states
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CST Pathways:
B Cell Receptor Signaling
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GPCR Signaling to MAPKs
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