WIZ May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization. Belongs to the krueppel C2H2-type zinc-finger protein family. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 17|17 B1
Cellular Component:  midbody; nucleoplasm; nucleus
Molecular Function:  DNA-binding transcription factor activity; metal ion binding; nucleic acid binding; protein binding; SET domain binding
Biological Process:  positive regulation of nuclear cell cycle DNA replication; protein heterotrimerization; protein stabilization; regulation of transcription, DNA-templated
Reference #:  O88286 (UniProtKB)
Alt. Names/Synonyms: Protein Wiz; widely-interspaced zinc finger motifs; Widely-interspaced zinc finger-containing protein; Wiz
Gene Symbols: Wiz
Molecular weight: 184,291 Da
Basal Isoelectric point: 6.54  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene