B4GALNT3 Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'-diacetyllactosediamine formation on gastric mucosa. Belongs to the chondroitin N-acetylgalactosaminyltransferase family. Highly expressed in testis, colon and stomach. Weakly expressed in other tissues. Note: This description may include information from UniProtKB.
Protein type: EC; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 12p13.33
Cellular Component:  Golgi cisterna membrane; integral component of membrane
Molecular Function:  acetylgalactosaminyltransferase activity; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
Reference #:  Q6L9W6 (UniProtKB)
Alt. Names/Synonyms: B4GalNAcT3; B4GALNT3; B4GN3; beta-1,4-N-acetyl-galactosaminyl transferase 3; beta-1,4-N-acetyl-galactosaminyltransferase 3; Beta-1,4-N-acetylgalactosaminyltransferase 3; Beta-1,4-N-acetylgalactosaminyltransferase III; Beta4GalNAc-T3; Beta4GalNAcT3; FLJ16224; FLJ40362; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2; NGalNAc-T2
Gene Symbols: B4GALNT3
Molecular weight: 114,975 Da
Basal Isoelectric point: 7.07  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB