PATZ1 Transcriptional repressor. Belongs to the krueppel C2H2-type zinc-finger protein family. Ubiquitous. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  chromatin binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; RNA polymerase II proximal promoter sequence-specific DNA binding
Biological Process:  male gonad development; negative regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; spermatogenesis; T cell differentiation
Reference #:  Q9HBE1 (UniProtKB)
Alt. Names/Synonyms: BTB-POZ domain zinc finger transcription factor; BTB/POZ domain zinc finger transcription factor; dJ400N23; MAZ-related factor; MAZR; PATZ; PATZ1; POZ (BTB) and AT hook containing zinc finger 1; POZ-, AT hook-, and zinc finger-containing protein 1; POZ-AT hook-zinc finger protein; POZ/BTB and AT hook containing zinc finger 1; Protein kinase A RI subunit alpha-associated protein; RIAZ; ZBTB19; Zinc finger and BTB domain-containing protein 19; Zinc finger protein 278; Zinc finger sarcoma gene protein; ZNF278; ZSG
Gene Symbols: PATZ1
Molecular weight: 74,060 Da
Basal Isoelectric point: 8.71  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB