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PGAM1
Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. Expressed in the liver and brain. Not found in the muscle. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 3.1.3.13; EC 5.4.2.11; EC 5.4.2.4; Isomerase; Phosphatase (non-protein) |
| Chromosomal Location of rat Ortholog: 1q54 |
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Cellular Component:
cytoplasm; cytosol; nucleus
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Molecular Function:
bisphosphoglycerate mutase activity; hydrolase activity; phosphoglycerate mutase activity; protein kinase binding
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Biological Process:
glycolytic process; regulation of glycolytic process; regulation of pentose-phosphate shunt; respiratory burst
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Reference #:
P25113
(UniProtKB)
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Alt. Names/Synonyms: BPG-dependent PGAM 1; PGAM-B; Pgam1; Pgmut; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); Phosphoglycerate mutase isozyme B
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Gene Symbols: Pgam1
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Molecular weight:
28,832 Da
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Basal Isoelectric point:
6.67
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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