PGAM1 Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. Expressed in the liver and brain. Not found in the muscle. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 3.1.3.13; EC 5.4.2.11; EC 5.4.2.4; Isomerase; Phosphatase (non-protein)
Chromosomal Location of Human Ortholog: 1q54
Cellular Component:  cytoplasm; cytosol; nucleus
Molecular Function:  bisphosphoglycerate mutase activity; hydrolase activity; phosphoglycerate mutase activity; protein kinase binding
Biological Process:  glycolytic process; regulation of glycolytic process; regulation of pentose-phosphate shunt; respiratory burst
Reference #:  P25113 (UniProtKB)
Alt. Names/Synonyms: BPG-dependent PGAM 1; PGAM-B; Pgam1; Pgmut; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); Phosphoglycerate mutase isozyme B
Gene Symbols: Pgam1
Molecular weight: 28,832 Da
Basal Isoelectric point: 6.67  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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PGAM1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene