BRD3 Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: ATYPICAL group; BRD family; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, atypical
Chromosomal Location of human Ortholog: 9q34.2
Cellular Component:  nucleus
Molecular Function:  chromatin binding; lysine-acetylated histone binding; protein binding
Biological Process:  chromatin organization; regulation of transcription by RNA polymerase II
Reference #:  Q15059 (UniProtKB)
Alt. Names/Synonyms: BRD3; bromodomain containing 3; bromodomain-containing 3; Bromodomain-containing protein 3; FLJ23227; FLJ41328; KIAA0043; ORFX; RING3-like protein; RING3L
Gene Symbols: BRD3
Molecular weight: 79,542 Da
Basal Isoelectric point: 9.39  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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BRD3

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein