ADPGK Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency. Belongs to the ADP-dependent glucokinase family. 6 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.1.147; Kinase, other; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9|9 B
Cellular Component:  endoplasmic reticulum; extracellular region
Molecular Function:  ADP-specific glucokinase activity; kinase activity; metal ion binding; phosphotransferase activity, alcohol group as acceptor; transferase activity
Biological Process:  carbohydrate metabolic process; glucose metabolic process; glycolytic process; phosphorylation
Reference #:  Q8VDL4 (UniProtKB)
Alt. Names/Synonyms: 2610017G09Rik; ADP-dependent glucokinase; ADP-GK; ADPGK; ATP-dependent glucokinase; C77577
Gene Symbols: Adpgk
Molecular weight: 53,902 Da
Basal Isoelectric point: 5.37  Predict pI for various phosphorylation states
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ADPGK

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene