ABCB7 Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins. Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, ABC family
Chromosomal Location of rat Ortholog: Xq22
Cellular Component:  integral component of membrane; mitochondrial inner membrane
Molecular Function:  ATP binding; ATPase activity, coupled to transmembrane movement of substances
Biological Process:  cellular iron ion homeostasis; transmembrane transport
Reference #:  Q704E8 (UniProtKB)
Alt. Names/Synonyms: ABC transporter 7 protein; Abcb7; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette, sub-family B, member 7, mitochondrial
Gene Symbols: Abcb7
Molecular weight: 82,558 Da
Basal Isoelectric point: 9.35  Predict pI for various phosphorylation states
Select Structure to View Below

ABCB7

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene