K83 Belongs to the intermediate filament family. Synthesis begins in the cortex 10-15 cell layers above the apex of the dermal papilla and ends abruptly in the middle of the cortex. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component:  cytosol; keratin filament
Molecular Function:  protein binding; structural molecule activity
Biological Process:  aging; cornification; epidermis development; hair cycle; keratinization
Disease: Erythrokeratodermia Variabilis Et Progressiva 5; Monilethrix
Reference #:  P78385 (UniProtKB)
Alt. Names/Synonyms: EKVP5; Hair keratin K2.10; hard keratin, type II, 3; Hb-3; HB3; hHb3; K83; keratin 83; keratin 83, type II; keratin, hair, basic, 3; Keratin, type II cuticular Hb3; keratin-83; KRT83; KRTHB3; MNLIX; type II hair keratin Hb3; type-II keratin Kb23
Gene Symbols: KRT83
Molecular weight: 54,195 Da
Basal Isoelectric point: 5.54  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein