Kv1.7 Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.7/KCNA7 sub-subfamily. Highly expressed in skeletal muscle, heart and kidney. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, multi-pass
Chromosomal Location of human Ortholog: 19q13.33
Cellular Component:  plasma membrane
Biological Process:  protein homooligomerization; regulation of ion transmembrane transport
Reference #:  Q96RP8 (UniProtKB)
Alt. Names/Synonyms: HAK6; KCNA7; Kv1.7; potassium channel, voltage gated shaker related subfamily A, member 7; Potassium voltage-gated channel subfamily A member 7; potassium voltage-gated channel, shaker-related subfamily, member 7; voltage-dependent potassium channel Kv1.7; voltage-gated potassium channel KCNA7; voltage-gated potassium channel subunit Kv1.7
Gene Symbols: KCNA7
Molecular weight: 50,559 Da
Basal Isoelectric point: 7.03  Predict pI for various phosphorylation states
Select Structure to View Below

Kv1.7

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein