Ugt1a2 UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family. Note: This description may include information from UniProtKB.
Protein type: EC 2.4.1.17; Membrane protein, integral; Transferase
Chromosomal Location of mouse Ortholog: 1|1 D
Cellular Component:  endoplasmic reticulum; integral component of membrane; intracellular membrane-bounded organelle; membrane
Molecular Function:  enzyme binding; glucuronosyltransferase activity; protein heterodimerization activity; protein homodimerization activity; retinoic acid binding; transferase activity; transferase activity, transferring glycosyl groups; transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity
Biological Process:  cellular glucuronidation; flavonoid glucuronidation; xenobiotic glucuronidation
Reference #:  P70691 (UniProtKB)
Alt. Names/Synonyms: bilirubin specific; Bilirubin-specific UDPGT; OTTMUSP00000022760; UD12; UDP glucuronosyltransferase 1 family, polypeptide A2; UDP-glucuronosyltransferase 1 family, member 2; UDP-glucuronosyltransferase 1 family, polypeptide A2; UDP-glucuronosyltransferase 1-2; UDP-glucuronosyltransferase 1A2; UDPGT; UDPGT 1-2; Ugt1; UGT1*0; UGT1*2; UGT1-02; UGT1.2; Ugt1a2; UGT1A2; UGT1A3
Gene Symbols: Ugt1a2
Molecular weight: 60,285 Da
Basal Isoelectric point: 8.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Ugt1a2

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein