Ugt1a2
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family. Note: This description may include information from UniProtKB.
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Protein type: EC 2.4.1.17; Membrane protein, integral; Transferase |
Chromosomal Location of mouse Ortholog: 1|1 D |
Cellular Component:
endoplasmic reticulum; intracellular membrane-bounded organelle; membrane
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Molecular Function:
enzyme binding; glucuronosyltransferase activity; glycosyltransferase activity; protein heterodimerization activity; protein homodimerization activity; retinoic acid binding; transferase activity; UDP-glycosyltransferase activity
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Biological Process:
cellular glucuronidation
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Reference #:
P70691
(UniProtKB)
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Alt. Names/Synonyms: bilirubin specific; Bilirubin-specific UDPGT; OTTMUSP00000022760; UD12; UDP glucuronosyltransferase 1 family, polypeptide A2; UDP-glucuronosyltransferase 1 family, member 2; UDP-glucuronosyltransferase 1 family, polypeptide A2; UDP-glucuronosyltransferase 1-2; UDP-glucuronosyltransferase 1A2; UDPGT; UDPGT 1-2; Ugt1; UGT1*0; UGT1*2; UGT1-02; UGT1.2; Ugt1a2; UGT1A2; UGT1A3
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Gene Symbols: Ugt1a2
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Molecular weight:
60,285 Da
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Basal Isoelectric point:
8.3
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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