ENTH
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. Belongs to the epsin family. Ubiquitously expressed at low to intermediate levels. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis |
Chromosomal Location of rat Ortholog: 10q21 |
Cellular Component:
clathrin-coated vesicle; Golgi apparatus; intracellular membrane-bounded organelle; membrane; nucleoplasm
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Molecular Function:
clathrin binding
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Biological Process:
clathrin coat assembly
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Reference #:
Q6DGF2
(UniProtKB)
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Alt. Names/Synonyms: Clathrin interactor 1; Clint; Enth; Enthoprotin; Epn4; epsin 4
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Gene Symbols: Clint1
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Molecular weight:
52,140 Da
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Basal Isoelectric point:
5.88
Predict pI for various phosphorylation states
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