COX4NB
Belongs to the EMC8/EMC9 family. Expressed in liver, pancreas, heart, lung, kidney, brain, skeletal muscle, and placenta. Expression levels are highest in pancreas and moderate in heart, skeletal muscle, and placenta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Mitochondrial |
Chromosomal Location of human Ortholog: 16q24.1 |
Cellular Component:
cytoplasm; EMC complex; endoplasmic reticulum; Golgi apparatus
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Molecular Function:
membrane insertase activity; protein binding
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Biological Process:
protein insertion into ER membrane by stop-transfer membrane-anchor sequence; tail-anchored membrane protein insertion into ER membrane
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Reference #:
O43402
(UniProtKB)
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Alt. Names/Synonyms: C16orf2; C16orf4; COX4 neighbor; COX4AL; COX4NB; CX4NB; EMC8; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158, member B; Neighbor of COX4; NOC4; Protein FAM158B
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Gene Symbols: EMC8
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Molecular weight:
23,773 Da
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Basal Isoelectric point:
5.92
Predict pI for various phosphorylation states
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