SFR1 Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1. Belongs to the SFR1/MEI5 family. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 10q25.1
Cellular Component:  centrosome; nucleolus; nucleoplasm; nucleus; Swi5-Sfr1 complex
Molecular Function:  nuclear receptor coactivator activity; protein binding
Biological Process:  cellular response to estrogen stimulus; double-strand break repair via homologous recombination; positive regulation of DNA-templated transcription
Reference #:  Q86XK3 (UniProtKB)
Alt. Names/Synonyms: bA373N18.1; C10orf78; MEI5; MEI5 recombination repair protein homolog; Meiosis protein 5 homolog; MEIR5; RP11-373N18.1; SFR1; SWI5 dependent homologous recombination repair protein 1; Swi5-dependent recombination DNA repair protein 1 homolog; SWI5-dependent recombination repair 1; SWI5-dependent recombination repair protein 1
Gene Symbols: SFR1
Molecular weight: 28,262 Da
Basal Isoelectric point: 6.06  Predict pI for various phosphorylation states
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SFR1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein