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AHSP
Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. Belongs to the AHSP family. Expressed in blood and bone marrow. Note: This description may include information from UniProtKB.
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| Chromosomal Location of human Ortholog: 16p11.2 |
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Cellular Component:
cytoplasm; hemoglobin complex
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Molecular Function:
hemoglobin binding; protein binding; unfolded protein binding
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Biological Process:
erythrocyte differentiation; hemoglobin metabolic process; hemopoiesis; protein folding; protein stabilization
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Reference #:
Q9NZD4
(UniProtKB)
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Alt. Names/Synonyms: AHSP; alpha hemoglobin stabilising protein; alpha hemoglobin stabilizing protein; Alpha-hemoglobin-stabilizing protein; EDRF; ERAF; erythroid associated factor; erythroid differentiation associated factor; erythroid differentiation-related factor; erythroid-associated factor; OTTHUMP00000163295; Q9NZD4
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Gene Symbols: AHSP
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Molecular weight:
11,840 Da
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Basal Isoelectric point:
4.9
Predict pI for various phosphorylation states
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