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ZYG11BL
Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC. Belongs to the zyg-11 family. Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas. Note: This description may include information from UniProtKB.
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| Protein type: Ligase; Ubiquitin conjugating system |
| Chromosomal Location of human Ortholog: 9q34.11 |
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Cellular Component:
Cul2-RING ubiquitin ligase complex
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Biological Process:
positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein quality control for misfolded or incompletely synthesized proteins
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Reference #:
Q7Z7L7
(UniProtKB)
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Alt. Names/Synonyms: C9orf60; homolog of Zyg-11; Hzyg; Protein zer-1 homolog; RP11-545E17.4; zer-1 homolog; zer-1 homolog (C. elegans); ZER1; ZYG; ZYG homolog; Zyg-11 homolog B-like protein; zyg-11 related cell cycle regulator; Zyg11b-like protein; ZYG11BL
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Gene Symbols: ZER1
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Molecular weight:
88,169 Da
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Basal Isoelectric point:
5.43
Predict pI for various phosphorylation states
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