COX17 Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX. Belongs to the COX17 family. Note: This description may include information from UniProtKB.
Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial
Chromosomal Location of Human Ortholog: 3q13.33
Cellular Component:  cytoplasm; mitochondrial intermembrane space
Molecular Function:  copper chaperone activity; copper ion binding; cuprous ion binding; protein binding
Biological Process:  brain development; copper ion transport; generation of precursor metabolites and energy; heart development; mitochondrial respiratory chain complex IV assembly; positive regulation of cell proliferation; positive regulation of cytochrome-c oxidase activity
Reference #:  Q14061 (UniProtKB)
Alt. Names/Synonyms: COX17; COX17 cytochrome c oxidase assembly homolog (S. cerevisiae); Cytochrome c oxidase copper chaperone; human homolog of yeast mitochondrial copper recruitment; MGC104397; MGC117386
Gene Symbols: COX17
Molecular weight: 6,915 Da
Basal Isoelectric point: 6.8  Predict pI for various phosphorylation states
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COX17

Protein Structure Not Found.


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