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MOS
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Expressed specifically in testis during spermatogenesis. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.11.1; Kinase, protein; MOS family; Oncoprotein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of Human Ortholog: 5q12 |
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Cellular Component:
cytoplasm; cytosol
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Molecular Function:
ATP binding; MAP kinase kinase kinase activity; protein kinase activity; protein serine/threonine kinase activity
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Biological Process:
activation of MAPK activity; activation of MAPKK activity; chromatin organization; ERK1 and ERK2 cascade; establishment of meiotic spindle orientation; intracellular signal transduction; MAPK cascade; meiotic spindle organization; negative regulation of metaphase/anaphase transition of meiotic cell cycle; positive regulation of MAPK cascade; protein autophosphorylation; protein phosphorylation; regulation of meiotic nuclear division; spermatogenesis
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Reference #:
P00539
(UniProtKB)
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Alt. Names/Synonyms: c-mos; Moloney murine sarcoma viral (v-mos) oncogene homolog; Moloney sarcoma oncogene; Mos; Oocyte maturation factor mos; Proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; v-mos moloney murine sarcoma viral oncogene homolog
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Gene Symbols: Mos
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Molecular weight:
37,621 Da
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Basal Isoelectric point:
9.52
Predict pI for various phosphorylation states
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