MOS
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Expressed specifically in testis during spermatogenesis. Note: This description may include information from UniProtKB.
|
Protein type: EC 2.7.11.1; Kinase, protein; MOS family; Oncoprotein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor) |
Chromosomal Location of rat Ortholog: 5q12 |
Cellular Component:
cytoplasm
|
Molecular Function:
ATP binding; MAP kinase kinase kinase activity; protein kinase activity; protein serine kinase activity; protein serine/threonine kinase activity
|
Biological Process:
chromatin organization; ERK1 and ERK2 cascade; establishment of meiotic spindle orientation; intracellular signal transduction; MAPK cascade; meiotic spindle organization; negative regulation of metaphase/anaphase transition of meiotic cell cycle; positive regulation of MAPK cascade; protein autophosphorylation; protein phosphorylation; regulation of meiotic nuclear division; signal transduction; spermatogenesis
|
Reference #:
P00539
(UniProtKB)
|
Alt. Names/Synonyms: c-mos; Moloney murine sarcoma viral (v-mos) oncogene homolog; Moloney sarcoma oncogene; Mos; Oocyte maturation factor mos; Proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; v-mos moloney murine sarcoma viral oncogene homolog
|
Gene Symbols: Mos
|
Molecular weight:
37,621 Da
|
Basal Isoelectric point:
9.52
Predict pI for various phosphorylation states
|