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SLC39A12
Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. Belongs to the ZIP transporter (TC 2.A.5) family. Expressed in brain and eye. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Membrane protein, multi-pass |
| Chromosomal Location of mouse Ortholog: 2|2 A2 |
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Cellular Component:
membrane; perinuclear region of cytoplasm; plasma membrane
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Molecular Function:
metal ion transmembrane transporter activity; monoatomic cation:bicarbonate symporter activity; zinc ion transmembrane transporter activity
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Biological Process:
metal ion transport; positive regulation of sprouting angiogenesis; regulation of microtubule polymerization; regulation of neuron projection development; signal transduction; transmembrane transport; zinc ion import across plasma membrane
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Reference #:
Q5FWH7
(UniProtKB)
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Alt. Names/Synonyms: AW046938; Gm731; MGC102235; S39AC; Slc39a12; solute carrier family 39 (zinc transporter), member 12; Solute carrier family 39 member 12; Zinc transporter ZIP12; ZIP-12; Zip12; Zrt- and Irt-like protein 12
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Gene Symbols: Slc39a12
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Molecular weight:
76,215 Da
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Basal Isoelectric point:
5.47
Predict pI for various phosphorylation states
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