SYDE2 GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho
Chromosomal Location of Human Ortholog: 1p22.3
Cellular Component:  cytosol
Molecular Function:  GTPase activator activity
Biological Process:  activation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction
Reference #:  Q5VT97 (UniProtKB)
Alt. Names/Synonyms: FLJ13815; Protein syd-1 homolog 2; Rho GTPase-activating protein SYDE2; RP11-33E12.1; SYDE2; synapse defective 1, Rho GTPase, homolog 2 (C. elegans); Synapse defective protein 1 homolog 2
Gene Symbols: SYDE2
Molecular weight: 133,230 Da
Basal Isoelectric point: 8.83  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene