ASB6 iso2 Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the ankyrin SOCS box (ASB) family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component:  cytosol
Molecular Function:  protein binding
Biological Process:  intracellular signal transduction; post-translational protein modification; protein ubiquitination
Reference #:  Q9NWX5-2 (UniProtKB)
Alt. Names/Synonyms: ankyrin repeat and SOCS box containing 6; Ankyrin repeat and SOCS box protein 6; ankyrin repeat and SOCS box protein 6 isoform 2; ankyrin repeat and SOCS box-containing 6; ASB-6; ASB6; ASB6 iso2; FLJ20548; MGC1024; OTTHUMP00000022342; OTTHUMP00000022343; Q9NWX5-2
Gene Symbols: ASB6
Molecular weight: 22,373 Da
Basal Isoelectric point: 8.73  Predict pI for various phosphorylation states
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ASB6 iso2

Protein Structure Not Found.

Cross-references to other databases:  cBioPortal  |  Wikipedia  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein