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NPFFR1
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
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| Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
| Chromosomal Location of human Ortholog: 10q22.1 |
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Cellular Component:
cilium; plasma membrane
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Molecular Function:
G protein-coupled receptor activity; neuropeptide receptor activity; peptide binding; protein binding
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Biological Process:
cellular response to hormone stimulus; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway
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Reference #:
Q9GZQ6
(UniProtKB)
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Alt. Names/Synonyms: FLJ10751; G protein-coupled receptor 147; G-protein coupled receptor 147; GPR147; neuropeptide FF 1; Neuropeptide FF receptor 1; NPFF1; NPFF1R1; NPFFR1; OT7T022; RFamide-related peptide receptor OT7T022
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Gene Symbols: NPFFR1
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Molecular weight:
47,819 Da
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Basal Isoelectric point:
9.54
Predict pI for various phosphorylation states
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