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TBCK iso3
Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization. Belongs to the protein kinase superfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Kinase, protein; Motility/polarity/chemotaxis; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of mouse Ortholog: 3|3 G3 |
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Cellular Component:
cytoplasm; cytoskeleton; midbody; mitotic spindle
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Molecular Function:
ATP binding; GTPase activator activity; protein kinase activity
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Biological Process:
actin cytoskeleton organization; activation of GTPase activity; cell population proliferation; protein phosphorylation; regulation of TOR signaling
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Reference #:
Q8BM85-3
(UniProtKB)
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Alt. Names/Synonyms: 1700120J03Rik; 9430001M19; A630047E20Rik; C030007I09Rik; TBC domain-containing protein kinase-like protein; TBC1 domain containing kinase; Tbck; Tbckl
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Gene Symbols: Tbck
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Molecular weight:
86,371 Da
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Basal Isoelectric point:
5.79
Predict pI for various phosphorylation states
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