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TMIGD1
May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral |
| Chromosomal Location of mouse Ortholog: 11|11 B5 |
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Cellular Component:
adherens junction; cell surface; cytoplasm; cytosol; membrane; mitochondrion; neuron projection; plasma membrane
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Molecular Function:
cell adhesion mediator activity; cell-cell adhesion mediator activity; protein homodimerization activity
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Biological Process:
brush border assembly; cell aggregation; cell migration; cell-cell adhesion; cell-cell junction organization; cellular response to hydroperoxide; intestinal epithelial cell maturation; intestinal epithelial cell migration; negative regulation of apoptotic process; negative regulation of epithelial cell proliferation; protein localization; regulation of cell migration; regulation of cell population proliferation; regulation of cyclin-dependent protein kinase activity; regulation of membrane permeability; response to nutrient
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Reference #:
Q9D7L8
(UniProtKB)
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Alt. Names/Synonyms: 2010002A20Rik; OTTMUSP00000006553; TMIG1; Tmigd; Tmigd1; transmembrane and immunoglobulin domain containing 1; Transmembrane and immunoglobulin domain-containing protein 1
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Gene Symbols: Tmigd1
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Molecular weight:
29,051 Da
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Basal Isoelectric point:
8.08
Predict pI for various phosphorylation states
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