CTTNBP2 Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal muscle and placenta. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Vesicle
Chromosomal Location of human Ortholog: 7q31.31
Cellular Component:  cell cortex; dendritic spine; glutamatergic synapse; postsynaptic actin cytoskeleton; synaptic vesicle
Molecular Function:  protein binding; SH3 domain binding
Biological Process:  brain development; regulation of modification of postsynaptic actin cytoskeleton; regulation of synapse organization
Reference #:  Q8WZ74 (UniProtKB)
Alt. Names/Synonyms: C7orf8; cortactin binding protein 2; Cortactin-binding protein 2; CORTBP2; CORTBP2, C7orf8; CTTB2; CTTNBP2; FLJ34229; KIAA1758; MGC104579; Orf4
Gene Symbols: CTTNBP2
Molecular weight: 181,051 Da
Basal Isoelectric point: 8.23  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene