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CTTNBP2
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal muscle and placenta. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Vesicle |
| Chromosomal Location of human Ortholog: 7q31.31 |
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Cellular Component:
cell cortex; dendritic spine; glutamatergic synapse; postsynaptic actin cytoskeleton; synaptic vesicle
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Molecular Function:
protein binding; SH3 domain binding
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Biological Process:
brain development; regulation of modification of postsynaptic actin cytoskeleton; regulation of synapse organization
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Reference #:
Q8WZ74
(UniProtKB)
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Alt. Names/Synonyms: C7orf8; cortactin binding protein 2; Cortactin-binding protein 2; CORTBP2; CORTBP2, C7orf8; CTTB2; CTTNBP2; FLJ34229; KIAA1758; MGC104579; Orf4
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Gene Symbols: CTTNBP2
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Molecular weight:
181,051 Da
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Basal Isoelectric point:
8.23
Predict pI for various phosphorylation states
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