STX3 Potentially involved in docking of synaptic vesicles at presynaptic active zones. Belongs to the syntaxin family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 11q12.1
Cellular Component:  apical plasma membrane; azurophil granule; cell-cell junction; dendrite; glutamatergic synapse; growth cone; lamellipodium; melanosome; neuron projection; plasma membrane; Schaffer collateral - CA1 synapse; SNARE complex; specific granule; vacuole; zymogen granule membrane
Molecular Function:  arachidonic acid binding; protein binding
Biological Process:  cytokine-mediated signaling pathway; long-term synaptic potentiation; neuron projection development; positive regulation of cell adhesion; positive regulation of cell proliferation; positive regulation of chemotaxis; positive regulation of protein localization to cell surface; positive regulation of protein localization to plasma membrane; synaptic vesicle docking
Reference #:  Q13277 (UniProtKB)
Alt. Names/Synonyms: STX3; STX3A; syntaxin 3; syntaxin 3A; Syntaxin-3
Gene Symbols: STX3
Molecular weight: 33,155 Da
Basal Isoelectric point: 5.31  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene