SALL3
Probable transcription factor. Belongs to the sal C2H2-type zinc-finger protein family. Widely expressed in adult with highest levels in heart. Expressed in fetal brain (in neurons of hippocampus, cortex, mediodorsal and ventrolateral thalamic nuclei, putamen, cerebellum and brainstem). 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: C2H2-type zinc finger protein; Motility/polarity/chemotaxis |
Chromosomal Location of mouse Ortholog: 18|18 E3 |
Cellular Component:
nucleus
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Molecular Function:
DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding
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Biological Process:
forelimb morphogenesis; hindlimb morphogenesis; negative regulation of smoothened signaling pathway; olfactory bulb interneuron development; regulation of transcription by RNA polymerase II; smoothened signaling pathway
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Reference #:
Q62255
(UniProtKB)
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Alt. Names/Synonyms: B130022O04Rik; Msa; MSal; Msal-1; Sal; sal-like 3; sal-like 3 (Drosophila); Sal-like protein 3; Sall3; Salt; Spalt; spalt like transcription factor 3; Spalt-like protein 3
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Gene Symbols: Sall3
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Molecular weight:
138,760 Da
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Basal Isoelectric point:
6.78
Predict pI for various phosphorylation states
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