NRBP1 May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Ubiquitously expressed in all tissues examined with high levels in the testis. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; NRBP family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 5|5 B1
Cellular Component:  cell projection; cytoplasm; endomembrane system; membrane; perinuclear region of cytoplasm
Molecular Function:  identical protein binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity
Biological Process:  ER to Golgi vesicle-mediated transport; intracellular signal transduction
Reference #:  Q99J45 (UniProtKB)
Alt. Names/Synonyms: B230344L17Rik; HLS7-interacting protein kinase; Madm; MGC6961; MLF1 adapter molecule; Nrbp; Nrbp1; nuclear receptor binding protein 1; Nuclear receptor-binding protein; OTTMUSP00000025666
Gene Symbols: Nrbp1
Molecular weight: 59,866 Da
Basal Isoelectric point: 5.02  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  KinBase  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein