NRBP1 May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Ubiquitously expressed in all tissues examined with high levels in the testis. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; NRBP family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 2p23.3
Cellular Component:  cell cortex; endomembrane system; lamellipodium; membrane; nucleoplasm
Molecular Function:  ATP binding; protein binding; protein homodimerization activity
Biological Process:  ER to Golgi vesicle-mediated transport; transcription initiation from RNA polymerase II promoter
Reference #:  Q9UHY1 (UniProtKB)
Alt. Names/Synonyms: BCON3; FLJ27109; FLJ35541; MADM; MUDPNP; multiple domain putative nuclear protein; myeloid leukemia factor 1 adaptor molecule; NRBP; NRBP1; nuclear receptor binding protein 1; Nuclear receptor-binding protein
Gene Symbols: NRBP1
Molecular weight: 59,845 Da
Basal Isoelectric point: 5.02  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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