NHLH1
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system. Note: This description may include information from UniProtKB.
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Chromosomal Location of mouse Ortholog: 1 H3|1 79.54 cM |
Cellular Component:
nucleus
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Molecular Function:
DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding
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Biological Process:
cell differentiation; multicellular organism development; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II
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Reference #:
Q02576
(UniProtKB)
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Alt. Names/Synonyms: bHLHa; bHLHa35; Helix-loop-helix protein 1; HELIX-LOOP-HELIX PROTEIN 1 (HEN1) (NSCL); Hen; HEN-1; Hen1; Nescient helix loop helix 1; Nhlh1; Nscl; NSCL-1; Tal2
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Gene Symbols: Nhlh1
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Molecular weight:
14,830 Da
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Basal Isoelectric point:
8.66
Predict pI for various phosphorylation states
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