PIGS Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. Belongs to the PIGS family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component:  endoplasmic reticulum membrane; GPI-anchor transamidase complex
Molecular Function:  protein binding
Biological Process:  attachment of GPI anchor to protein
Disease: Glycosylphosphatidylinositol Biosynthesis Defect 18
Reference #:  Q96S52 (UniProtKB)
Alt. Names/Synonyms: DKFZp686K20216; FLJ45226; GPI transamidase component PIG-S; GPI transamidase subunit; GPIBD18; phosphatidylinositol glycan anchor biosynthesis class S; phosphatidylinositol glycan anchor biosynthesis, class S; phosphatidylinositol glycan, class S; Phosphatidylinositol-glycan biosynthesis class S protein; PIGS
Gene Symbols: PIGS
Molecular weight: 61,656 Da
Basal Isoelectric point: 6.05  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene