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PEAK1
Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling. Belongs to the protein kinase superfamily. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.10.2; Kinase, protein; NKF3 family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of human Ortholog: 15q24.3 |
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Cellular Component:
actin cytoskeleton; cytoplasm; focal adhesion
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Molecular Function:
ATP binding; identical protein binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein kinase activity
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Biological Process:
cell migration; focal adhesion assembly; peptidyl-tyrosine phosphorylation; protein autophosphorylation; protein phosphorylation; regulation of focal adhesion assembly; substrate adhesion-dependent cell spreading
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Reference #:
Q9H792
(UniProtKB)
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Alt. Names/Synonyms: FLJ21140; FLJ34483; Inactive tyrosine-protein kinase PEAK1; KIAA2002; NKF3 kinase family member; PEAK1; pseudopodium enriched atypical kinase 1; Pseudopodium-enriched atypical kinase 1; SG269; SGK269; Sugen kinase 269; Tyrosine-protein kinase SgK269
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Gene Symbols: PEAK1
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Molecular weight:
193,106 Da
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Basal Isoelectric point:
6.46
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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